Genome stability, transcription and RNA-based control, cell fate

Faculty in the group of " Genome stability, transcription and RNA-based control, cell fate " investigates a spectrum of cellular and molecular processes regulating the mammalian genome in healthy cells, as well as how they may go wrong in diseased conditions. These include studies of epigenetic regulation and transcription, telomere, DNA recombination, RNA transport and editing, non-coding RNAs such as microRNAs, translation, and cell fate control. These processes together mediate a normal cell’s execution of its genome and to maintain its integrity.

Dysfunction in any of these processes often underlines important disease including cancers. Ultimately, these studies will address how this information may be applied in the development of more specific and selective therapeutic agents.

List of Faculty

Peter Bitterman     Colin Campbell         Greg Connell

Horace H. Loh       Dan Romero             Li-Na Wei;

Gibson Wood         Yan Zeng