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Department of Pharmacology


Pharmacology Graduate Faculty

Primary Appointment

 
Faculty name Research Interests
   
Colin Campbell, Ph.D.
Director of Graduate Studies		 Molecular mechanisms of DNA repair and genome instability in mammalian somatic cells.
   
Gregory Connell, Ph.D.  RNA editing in trypanosomes and mammalian iron homeostasis.
   
 Earl Dunham, Ph.D.  Synthesis and role of vasoactive autacoids in regulation of the peripheral circulation.
   
 Hiroshi Hiasa, Ph.D.  Molecular basis of the cytotoxicity of topoisomerase-targeted anticancer and antimicrobial drugs,
 as well as identification of the factors that affect global gene expression and genomic stability.
   
 Jordan Holtzman, M.D., Ph.D.  Biochemical problems in drug metabolism and drug toxicity.
   
 Ping-Yee Law, Ph.D.  Cellular regulation of opioid receptor signaling.
   
 Cheuk Leung, Ph.D.  Exploiting tissue homeostatic mechanisms to target tumor initiation and dormancy.
   
 Fang Li , Ph.D.  Structural biology of human diseases including virus infections, cancer, and abnormal blood pressure.
   
 Horace H. Loh, Ph.D.
 Regents Professor, Frederick and
 Alice Stark Professor		  Neurochemical mechanisms of opioids--major pain killers with addictive potential.
   
 Jonathan Marchant, Ph.D.
 Interim Head		  Spatial and temporal dynamics of intracellular Ca2+ signals.
   
 Sundaram Ramakrishnan, Ph.D.  Tumor angiogenesis – Antiangiogenic Gene Therapy.
   
 Daniel Romero, Ph.D.  Chromosome stability, telomerase structure and function, and gene amplification.
   
 Stanley Thayer, Ph.D.  Drugs that modulate neurotoxicity and neuronal signaling processes.
   
 Timothy Walseth, Ph.D.  Regulation of calcium mobilization by cyclic ADP-ribose and other nucleotides.
   
 Li-Na Wei, Ph.D.
 Director of Undergraduate Studies		  Regulatory pathways and mechanisms for adipocyte and neuronal differentiation, and in metabolic diseases.
   
 Kevin Wickman, Ph.D.  Mechanisms and consequences of cell inhibition
 triggered by neurotransmitters, hormones, and drugs of abuse.
   
 W. Gibson Wood, Ph.D.
  Regulation and function of cholesterol in brain, its role in neurodegenerative diseases and
  neuroprotective mechanisms of cholesterol lowering drugs.
   
Yan Zeng, Ph.D.  The biogenesis and function of regulatory RNAs.
   

Non-Primary Appointments

 
Faculty name Research Interests
   
Gavin Bart, M.D.  Treatment for substance abuse.
   
Peter Bitterman, M.D.  Translational Control of Cell Fate.
   
Frank Burton, Ph.D.  Transgenic modeling of cancer and neurological diseases.
   
Esam El-Fakahany, Ph.D.  Neuronal receptor modulation, mechanisms of receptor coupling to
 second messenger signal transduction pathways, and Alzheimer's disease.
   
Carolyn Fairbanks, Ph.D.  Development of novel compounds with a pharmacokinetic/dynamic profile
 ideal for spinal delivery for pain relief.
   
S. Hossein Fatemi, M.D., Ph.D. Biology and pharmacology of autism, schizophrenia, and mood disorders.
   
Jonathan Gewirtz, Ph.D.  Mechanisms of fear, anxiety, and drug withdrawal.
   
   
Stephen Hecht, Ph.D.  Tobacco Research.
   
Paulo Kofuji, Ph.D.  Identity, mechanisms of regulation and expression of
 potassium and water channels in glial cells.
   
Carol Lange, Ph.D.  Signal Transduction in Breast Cancer.
   
Michael K. Lee, Ph.D.  Alzheimer’s and Parkinson’s Disease: Mechanisms and Therapies
   
Ling Li, Ph.D.  Connections between Alzheimer’s disease and cardiovascular disease/Diabetes: Pathogenesis and Therapies
   
Louis Mansky, Ph.D.  Cell and molecular biology of HIV and HTLV; HIV drug resistance;
 HTLV particle assembly and release; Evolution of emerging viruses.
   
Steven Patterson, Ph.D.  Anti-microbial drugs, cancer therapy, antiviral therapy, cyanide antidotes,
  synthetic methods.
   
Paul Pentel, M.D.  Mechanisms and treatment of drug toxicity.
   
Philip Portoghese, Ph.D.  Design and synthesis of ligands as probes to investigate pharmacologic receptors.
   
Lincoln Potter, Ph.D.  Signal Transduction, Natriuretic Peptides, Guanylyl Cyclase Receptors and cGMP.
   
Sabita Roy, Ph.D.  Molecular mechanism of morphine-induced immunosuppression.
   
Deepali Sachdev, Ph.D.  Regulation of breast cancer biology and metastasis by insulin-like
  growth factor signaling and insulin like growth factor receptor
  targeted therapy for breast cancer.
   
Ashok Saluja, Ph.D.  Pancreatic cancer; mechanisms and treatment strategies for pain.
   
Subbaya Subramanian, Ph.D.  MicroRNA gene regulatory networks in cancer.
   
Daniel Vallera, Ph.D.  Immunology, Bone Marrow Transplantation, and 
Cancer Research.
   
Elizabeth Wattenberg, Ph.D.  Mechanisms by which chemical carcinogens modulate signal transduction pathways.
   
George Wilcox, Ph.D.  Cellular and molecular mechanisms of neural plasticity underlying chronic
 pain and analgesic tolerance and dependence in the nervous system.
   
Douglas Yee, M.D.  Role of insulin-like growth factors in breast cancer biology.
   
LiLian Yuan, Ph.D.  Mechanisms of neural plasticity; dendritic function in neuronal information processing.
   

Adjunct Faculty Appointments

  
Faculty name Research Interests
   
Marco Pravetoni, Ph.D.  Development of novel therapies for prescription opiod abuse: vaccines and medications.
   
   
   

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