Pharmacology Faculty

Fang Li , Ph.D.
Assistant Professor of Pharmacology

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Publications

Research Interests

We study the structural basis for the invasion and replication mechanisms of human viral pathogens.

Using SARS, human common colds, and other important viral pathogens as sample species, we ask three questions. First, how do viruses recognize their receptors and invade host cells? Second, once inside the host cells, how do viruses replicate themselves? Third, how can we inhibit the invasion and replication of viruses? We address these questions using X-ray crystallography, electron microscopy, molecular biology, and protein biochemistry.

Our research primarily targets two proteins: the glycoproteins on the viral surface that guide cell entry, and the polymerases that replicate viral genomes inside cells.

To learn more about the research in the laboratory visit our webpage.