2005 Pharmacology Seminar Series

Spring Summer Fall

Spring 2005

January 21, 2005, 2-101 BSBE, 12:15 pm - Faculty Candidate
Inhibition of Pathogenic Protein-Protein Interactions with Bifunctional Small Molecules
JASON GESTWICKI, Ph.D.
Helen Hay Whitney Postdoctoral Fellow
Department of Pathology
Howard Hughes Medical Institute, Stanford School of Medicine
Hosted by: Dr. Jonathan Marchant (624-6687)
January 28, 2005, 2-101 BSBE, 12:15 pm - Faculty Candidate
Ligand-dependent and ligand-independent signal transduction and function of the Ret receptor tyrosine kinase
BRIAN PIERCHALA, Ph.D.
Research Instructor
Department of Molecular Biology & Pharmacology
Washington University School of Medicine-St. Louis
Hosted by: Dr. Stan Thayer (626-7049)

Wednesday, February 9, 2005, 2-101 BSBE, 10:15 am - Faculty Candidate
Neutrophil Polarity and Chemotaxis: Dissecting the Signaling Network
FEI WANG, Ph.D.
Postdoctoral Fellow
Department of Cellular & Molecular Pharmacology
University of California-San Francisco
Hosted by: Dr. Li-Na Wei (625-9402)

Wednesday, March 2, 2005, 2-101 BSBE, 10:15 am - Faculty Candidate
Intersectin (ITSN): a Nexus for the Regulation of Cell Growth, Differentiation and Cellular Signaling
JOHN P. O'BRYAN, Ph.D.
Investigator, Laboratory of Signal Transduction
National Institute of Environmental Health Sciences
Hosted by: Dr. Jonathan Marchant (624-6687)

March 11, 2005
Alzheimer’s dementia is due to faulty, ER, posttranslational protein processing
JORDAN HOLTZMAN, M.D, Ph.D.
Professor, Department of Pharmacology
University of Minnesota
Hosted by: Dr. Jordan Holtzman (612-725-2000 x3616)

Monday, March 14, 2005, 2-101 BSBE, 2:00 pm - Faculty Candidate
The biogenesis and function of human microRNAs
YAN ZENG, Ph.D.
Research Associate
Howard Hughes Medical Institute
Duke University
Hosted by: Dr. Sabita Roy (624-4615)

*RE-SCHEDULED*
Thursday, March 17, 2005, 2-101 BSBE, 11:45 am - Faculty Candidate
CaM Kinase II: Molecular Studies of a Memory Molecule
J. MICHAEL BRADSHAW, Ph.D.
Postdoctoral Fellow
Department of Molecular Pharmacology
Stanford University School of Medicine
Hosted by: Dr. Stan Thayer (626-7049)

March 25, 2005, 2-101 BSBE, 12:15 pm - Faculty Candidate
Protein Kinase D, a sensor for oxidative stress in cancer and age-related diseases
PETER STORZ, Ph.D.
Instructor
Department of Pathology
Beth Israel Deaconess Medical Center, Harvard Medical School
Hosted by: Dr. Sabita Roy (624-4615)

April 1, 2005
Cholesterol, statins and Alzheimer’s disease: What’s the connection?
BENJAMIN WOLOZIN, M.D., Ph.D.
Professor, Department of Pharmacology
Boston University School of Medicine
Hosted by: Dr. Gibson Wood (612-467-3303)

April 8, 2005
Convergence of anti-tumor signaling pathways and epigenetic drugs on TRAIL, a selective inducer of apoptosis in cancer cells
HINRICH GRONEMEYER, Ph.D.
Director of Research, Department of Cell Biology & Signal Transduction
IGBMC – France
Hosted by: Dr. Li-Na Wei (625-9402)

April 15, 2005
Role of intracellular Ca stores in HIV TAT-induced neuronal responses
NAE DUN, Ph.D.
Professor & Chairman, Department of Pharmacology
Temple University School of Medicine
Hosted by: Dr. Ping-Yee Law (626-6497)
*Co-sponsored by the Basic Research Center on the Molecular & Cell Biology of Drug Addiction (NIDA: DA11806)

April 22, 2005
Bile acids for the treatment of neurodegenerative diseases
CLIFFORD STEER, Ph.D.
Professor of Medicine and Genetics, Cell Biology, and Development
Director, Molecular Gastroenterology Program
University of Minnesota Medical School
Hosted by: Dr. Gibson Wood (612-467-3303)

April 29, 2005
Patterning and Formation of Neuromuscular Synapses
KUO-FEN LEE, Ph.D.
Associate Professor, Clayton Foundation Laboratories for Peptide Biology
The Salk Institute for Biological Studies
Hosted by: Dr. Ping-Yee Law (626-6497)
*Co-sponsored by the Basic Research Center on the Molecular & Cell Biology of Drug Addiction (NIDA: DA11806)

~~May 6, 2005~~ CANCELLED
Bacterial enterotoxins confer resistance to colorectal cancer
SCOTT WALDMAN, M.D., Ph.D., FCP
Samuel M.V. Hamilton Professor of Medicine &
Professor of Biochemistry and Molecular Pharmacology
Director of the Division of Clinical Pharmacology
Thomas Jefferson University
Hosted by: Dr. Lincoln Potter (624-7251)

~~May 6, 2005~~ - POSTPONED TO A LATER DATE
Opioid analgesia: Structural and functional implications of mu opioid receptor splice variants
GAVRIL PASTERNAK, M.D., Ph.D.
Member and Attending Neurologist
Head, Laboratory of Molecular Neuropharmacology
Memorial Sloan-Kettering Cancer Center
Professor of Neurology & Neuroscience, Pharmacology and Psychiatry
Weill College of Medicine of Cornell University
Hosted by: Dr. Ping-Yee Law (626-6497)
*Co-sponsored by the Basic Research Center on the Molecular & Cell Biology of Drug Addiction (NIDA: DA11806)

May 13, 2005, 2-137 Jackson Hall, 12:15 pm - Graduate Faculty Candidate
GSK and Bipolar disorder: Translating molecules to behavior
HAIM EINAT, Ph.D.
Assistant Professor, Dept of Pharmacy Practice and Pharmaceutical Sciences
College of Pharmacy
University of Minnesota-Duluth
Hosted by: Dr. Colin Campbell (625-8986)

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Summer 2005

Tuesday, July 5, 2005, 2-101 Hasselmo Hall, 12:15 pm - Faculty Candidate
P-glycoprotein ATPase Mechanism
GREGORY TOMBLINE, Ph.D.
Postdoctoral Fellow
Department of Biochemistry & Biophysics
University of Rochester Medical Center
Hosted by: Dr. Li-Na Wei (625-9402)

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Fall 2005

September 23
2005 F.E. Shideman-Sterling Lecture
Molecular Biology of Taste
CHARLES ZUKER, Ph.D.
Investigator, Howard Hughes Medical Institute
Professor, Division Of Biological Sciences
University of California-San Diego
Hosted by: Dr. Horace Loh (626-4460)

October 14
Cell and molecular biology of HIV and HTLV:
implications for drug resistance and drug design
LOUIS M. MANSKY, Ph.D.
Director, Institute for Molecular Virology
University of Minnesota
Hosted by: Dr. Colin Campbell (625-8986)

October 21
Dendritic mechanisms controlling membrane excitability and synaptic plasticity in hippocampus
LILIAN YUAN, Ph.D.
Associate Professor, Department of Neuroscience
University of Minnesota
Hosted by: Dr. Colin Campbell (625-8986)

October 28
Retinoids and Adipose Tissue4: New Insights from Mouse Models
WILLIAM BLANER, Ph.D.
Associate Professor, Nutritional Medicine
Columbia University, College of Physicians & Surgeons
Hosted by: Dr. Li-Na Wei (625-9402)

November 11
From bench to bedside: Development of novel diagnostics and therapeutics for GI malignancies
SCOTT WALDMAN, M.D., Ph.D., FCP
Samuel M.V. Hamilton Professor of Medicine &
Professor of Biochemistry and Molecular Pharmacology
Director of the Division of Clinical Pharmacology
Thomas Jefferson University
Hosted by: Dr. Lincoln Potter (624-7251)

November 18
A New Non-invasive Approach to Detect Organ Rejection by Cellular and Functional MRI
CHIEN HO, Ph.D.
Professor, Dept. of Biological Sciences
Carnegie Mellon University
Hosted by: Dr. Horace Loh (626-4460)

***RE-SCHEDULED***
Tuesday, December 13, 2-101 NHH, 2:00 pm - Faculty Candidate
Sfp Phosphopantetheinyl Transferase Catalyzed Chemical Biology – From Protein Labeling to Gene Profiling
JUN YIN, Ph.D.
Postdoctoral Research Fellow
Department of Biological Chemistry & Molecular Pharmacology
Harvard Medical School
Hosted by: Dr. Li-Na Wei (625-9402)

Wednesday, December 14, 2-101 NHH, 1:30 pm - Faculty Candidate
Too Much of a Good Thing? Regulation of Chemosensory Signal Transduction and Behavior in C. elegans
DENISE FERKEY, Ph.D.
Postdoctoral Fellow
Department of Pathology
Harvard Medical School & Massachusetts General Hospital Cancer Center
Hosted by: Dr. Tim Walseth (625-2627)

December 16
Title: To be Announced
GARY LANDRETH, Ph.D.
Professor of Neurosciences & Neurology
Alzheimer Research Laboratory
Case Western Reserve University
Hosted by: Dr. Gibson Wood (612-467-3303)

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